Your web browser is out of date

For the best experience, please upgrade. Learn more

Basil Essential Oil Shows DNA Protective Effects

Protective effect of basil (Basil c.t. Linalool Essential Oil) against oxidative DNA damage and mutagenesisBeri? T, Nikoli? B, Stanojevi? J, Vukovi?-Ga?i? B, Kne?evi?-Vuk?evi? J Faculty of Biology, Laboratory for Microbiology, University of Belgrade, Studentski trg 16, 11000 Belgrade, Serbia. Mutagenic and antimutagenic properties of essential oil (EO) of basil and its major constituent Linalool (ed. [...]

Protective effect of basil (Basil c.t. Linalool Essential Oil) against oxidative DNA damage and mutagenesis

Beri? T, Nikoli? B, Stanojevi? J, Vukovi?-Ga?i? B, Kne?evi?-Vuk?evi? J

Faculty of Biology, Laboratory for Microbiology, University of Belgrade, Studentski trg 16, 11000 Belgrade, Serbia.

Mutagenic and antimutagenic properties of essential oil (EO) of basil and its major constituent Linalool (ed. note: this is the type of Basil oil carried at Ananda), reported to possess antioxidative properties, were examined in microbial tests. In Salmonella/microsome and Escherichia. coli WP2 reversion assays both derivatives (0.25-2.0mul/plate) showed no mutagenic effect. Salmonella. typhimurium TA98, TA100 and TA102 strains displayed similar sensitivity to both basil derivatives as non-permeable E. coli WP2 strains IC185 and IC202 oxyR. Moreover, the toxicity of basil derivatives to WP2 strains did not depend on OxyR function. The reduction of t-BOOH-induced mutagenesis by EO and Linalool (30-60%) was obtained in repair proficient strains of the E. coli K12 assay (Nikoli?, B., Stanojevi?, J., Miti?, D., Vukovi?-Gaci?, B., Knezevi?-Vukcevi?, J., Simi?, D., 2004. Comparative study of the antimutagenic potential of vitamin E in different E. coli strains. Mutat. Res. 564, 31-38), as well as in E. coli WP2 IC202 strain. EO and Linalool reduced spontaneous mutagenesis in mismatch repair deficient E. coli K12 strains (27-44%). In all tests, antimutagenic effect of basil derivatives was comparable with that obtained with model antioxidant vitamin E. Linalool and vitamin E induced DNA strand breaks in Comet assay on S. cerevisiae 3A cells, but at non-genotoxic concentrations (0.075 and 0.025mug/ml, respectively) they reduced the number of H(2)O(2)-induced comets (45-70% Linalool and 80-93% vitamin E).

Obtained results indicate that antigenotoxic potential of basil derivatives could be attributed to their antioxidative properties.

Share Share

Discover how to enhance your life with Mother Nature’s remedies

We’ve got the blueprints for health, beauty, spirituality, and more..

Start Quiz

Transformative Times 9/27/2020

ANANDA CONTINUES JUST DIFFERENTLY You will soon see a slight change to our website. We  have decided to transition the online store to a resource and information site.So while you can not purchase products, you can still have access to the incredible depth of information!We have 16 years of research, and useful tidbits about Essentials oils, CO2 extracts, Carrier Oils and […]

In Eternal Memory of  Eric Cech, Ananda’s Founder 

    In Eternal Memory of Eric Cech, Ananda’s Founder “The best business model I can hope for is one that will run out of business.” – Eric Cech Eric’s business mindset was otherworldly. He admitted in casual conversation to his wife Anita one day: “The best business model I can hope for is one that […]

Thank You for Your Incredible Support

It Comes with the Greatest Pleasure To let You Know… that…Because of YOU Ananda has Managed to Survive one of the Most Uncertain Times of its Tenure  ~ We can not thank you enough for your enormous patience, understanding and support. From your incoming calls, comments on social media, direct messages across various channels, emails […]

CUSTOMER HEARTFELT RESPONSES

Here are a small fraction of the heartfelt responses we have received following the notice of our business closure and liquidation sale. We offer all of you a deserved shout out for being the improbable,  most essential, significant, factor in creating the Dream you are voicing to us: Hope for a Sustainable Future and Provider […]

Thank You For your Support

Thank You For your Support Since 2004 The Ananda Apothecary is Closing Business   SAD BUT TRUE As previously disclosed, The Ananda Apothecary has been greatly affected by to the global health situation. Bottom line is, we were increasing growing slim on product with no resupply any time soon. We are unable to get goods […]

Spring Cleaning Special

* SPRING CLEANING SPECIAL * *OFFERS VALID APRIL 24 – MAY 2, OR UNTIL SUPPLIES LAST. SOME RESTRICTIONS APPLY. WE’RE GIVING OILS AWAY Get Yours Today! WITH ANY PURCHASE THAT FITS YOUR BUDGET GET UP TO THREE OF YOUR ALL TIME FAVORITE OILS FREE *We have limited supplies due to overseas shipping restrictions. Order now while supplies last. ALSO […]