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Oregano Essential Oil Components of Carvacrol and Thymol Both Important
Editor’s note: This study evaluted the anti-microbial effects of the two primary constituents of oregano essential oil: Carvacrol and Thymol. While oregano is often marketed with the concentration of Carvacrol noted, it is important to recognize (and this is the case with almost ALL essential oils) that it is a synergy of the oil’s molecules, [...]
November 30 2007
Editor’s note: This study evaluted the anti-microbial effects of the two primary constituents of oregano essential oil: Carvacrol and Thymol. While oregano is often marketed with the concentration of Carvacrol noted, it is important to recognize (and this is the case with almost ALL essential oils) that it is a synergy of the oil’s molecules, not just a single isolated chemical, that produces the profound health effects.
A study of the minimum inhibitory concentration and mode of action of oregano essential oil, thymol and carvacrol.
AIMS: The minimum inhibitory concentration (MIC) of oregano essential oil (OEO) and two of its principle components, i.e. thymol and carvacrol, against Pseudomonas aeruginosa and Staphylococcus aureus was assessed by using an innovative technique. The mechanism of action of the above substances was also investigated. METHODS AND RESULTS: The applied technique uses 100-well microtitre plate and collects turbidimetric growth data. To produce the inhibition profiles, a wide range of concentrations were tested for each of the three compounds, as well as for carvacrol-thymol mixtures. Following a specific mathematical analysis of the observed inhibition profiles from all compounds, it was suggested that mixtures of carvacrol and thymol gave an additive effect and that the overall inhibition by OEO can be attributed mainly to the additive antimicrobial action of these two compounds. Addition of low amounts of each additive: (a) increased permeability of cells to the nuclear stain EB, (b) dissipated pH gradients as indicated by the CFDA-SE fluorescent probe irrespective of glucose availability and (c) caused leakage of inorganic ions. CONCLUSION: Mixing carvacrol and thymol at proper amounts may exert the total inhibition that is evident by oregano essential oil. Such inhibition is due to damage in membrane integrity, which further affects pH homeostasis and equilibrium of inorganic ions. SIGNIFICANCE AND IMPACT OF THE STUDY: The knowledge of extent and mode of inhibition of specific compounds, which are present in plant extracts, may contribute to the successful application of such natural preservatives in foods, since certain combinations of carvacrol-thymol provide as high inhibition as oregano essential oil with a smaller flavour impact.
ANANDA CONTINUES JUST DIFFERENTLY You will soon see a slight change to our website. We have decided to transition the online store to a resource and information site.So while you can not purchase products, you can still have access to the incredible depth of information!We have 16 years of research, and useful tidbits about Essentials oils, CO2 extracts, Carrier Oils and […]
In Eternal Memory of Eric Cech, Ananda’s Founder “The best business model I can hope for is one that will run out of business.” – Eric Cech Eric’s business mindset was otherworldly. He admitted in casual conversation to his wife Anita one day: “The best business model I can hope for is one that […]
We Want You To Know – We Have Heard You. Your sentiments are important to us. We are considering our next steps with YOU in mind. Dearest Ananda Customers~ Many of you have asked us if this closure is permanent, or if there is any way we may be able to remain open, or make […]
It Comes with the Greatest Pleasure To let You Know… that…Because of YOU Ananda has Managed to Survive one of the Most Uncertain Times of its Tenure ~ We can not thank you enough for your enormous patience, understanding and support. From your incoming calls, comments on social media, direct messages across various channels, emails […]
Here are a small fraction of the heartfelt responses we have received following the notice of our business closure and liquidation sale. We offer all of you a deserved shout out for being the improbable, most essential, significant, factor in creating the Dream you are voicing to us: Hope for a Sustainable Future and Provider […]
Thank You For your Support Since 2004 The Ananda Apothecary is Closing Business SAD BUT TRUE As previously disclosed, The Ananda Apothecary has been greatly affected by to the global health situation. Bottom line is, we were increasing growing slim on product with no resupply any time soon. We are unable to get goods […]
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