Your web browser is out of date

For the best experience, please upgrade. Learn more

Essential Oil Vapors Studied for Sedative Effects

It appears that mice get the same sort of jitters from caffeine that humans do. And they respond in a statistically significant manner to the sedative effects of essential oil vapors (as produced by aromatherapy diffusers). Here are a few studies of the effects ~ note that the effects of Lavender are confirmed, along with [...]

It appears that mice get the same sort of jitters from caffeine that humans do. And they respond in a statistically significant manner to the sedative effects of essential oil vapors (as produced by aromatherapy diffusers). Here are a few studies of the effects ~ note that the effects of Lavender are confirmed, along with Spikenard.

Study: Sedative effects of vapor inhalation of agarwood oil and spikenard extract and identification of their active components.

Takemoto H, Ito M, Shiraki T, Yagura T, Honda G. Department of Pharmacognosy, Graduate School of Pharmaceutical Science, Kyoto University, 46-29 Yoshida-Shimoadachi-cho, Sakyo-ku, Kyoto, 606-8501, Japan.

Agarwood oil and spikenard extract were examined for their sedative activity using a spontaneous vapor administration system. It was shown that inhalation of agarwood oil vapor sedated mice. The main volatile constituents of the oil were found to be benzylacetone [agarwood oil from a Hong Kong market (1)], or alpha-gurjunene and (+)-calarene [agarwood oil made in Vietnam (2)]. A hexane extract of spikenard contained a lot of calarene, and its vapor inhalation had a sedative effect on mice. Individual principles benzylacetone, calarene, and alpha-gurjunene were administered to mice, which reproduced the result of the corresponding oil or extract. However, the most effective dose of the compounds was lower than their original content in the oil and extract (benzylacetone 0.1%, calarene 0.17%, alpha-gurjunene 1.5%).

Study: Stimulative and sedative effects of essential oils upon inhalation in mice.

Lim WC, Seo JM, Lee CI, Pyo HB, Lee BC. R&D Center, Hanbul Cosmetics Co. Ltd., 72-7 Yongsung-ri, Samsung-Myun, Chungbuk 369-830, Korea.

This study investigated the stimulative or sedative effects of inhaling fragrant essential oils (EOs) by using a forced swimming test (FST) with mice. This behavioral test is commonly used to measure the effects of antidepressant drugs. The inhalation by mice of EOs, such as ginger oil (p<0.05), thyme oil (p<0.05), peppermint oil (p<0.05), cypress oil (p<0.01) lavender oil (p<0.01) and hyssop oil (p<0.01) increased the immobile state in mice that were treated with caffeine. The results of this study indicate that the inhalation of essential oils may induce stimulative or sedative effects in mice.

Study: Fragrance compounds and essential oils with sedative effects upon inhalation.

Buchbauer G, Jirovetz L, Jäger W, Plank C, Dietrich H. Institute of Pharmaceutical Chemistry, University of Vienna, Austria.

Fragrance compounds and essential oils with sedative effects influence the motility of mice in inhalation studies under standardized conditions. A significant drop in the motility of mice was registered following exposure to these fragrances. The same results were achieved when the mice were artificially induced into overagitation by intraperitoneal application of caffeine and subsequently subjected to inhalation of fragrance compounds and essential oils. These results proved the sedative effects of these fragrants via inhalative exposure in low concentrations. Blood samples were taken from the mice after a 1-h inhalation period. Chromatographic and spectroscopic methods were used to detect and characterize the actual effective compounds after solid-phase extraction. Serum concentrations of 42 different substances, including fragrance compounds, were found in low ranges (ng/mL serum). The results contribute to the correct interpretation of the term aromatherapy (i.e., a stimulating or sedative effect on the behaviour of individuals only upon inhalation of fragrance compounds).

Share Share

Discover how to enhance your life with Mother Nature’s remedies

We’ve got the blueprints for health, beauty, spirituality, and more..

Start Quiz

Transformative Times 9/27/2020

ANANDA CONTINUES JUST DIFFERENTLY You will soon see a slight change to our website. We  have decided to transition the online store to a resource and information site.So while you can not purchase products, you can still have access to the incredible depth of information!We have 16 years of research, and useful tidbits about Essentials oils, CO2 extracts, Carrier Oils and […]

In Eternal Memory of  Eric Cech, Ananda’s Founder 

    In Eternal Memory of Eric Cech, Ananda’s Founder “The best business model I can hope for is one that will run out of business.” – Eric Cech Eric’s business mindset was otherworldly. He admitted in casual conversation to his wife Anita one day: “The best business model I can hope for is one that […]

Thank You for Your Incredible Support

It Comes with the Greatest Pleasure To let You Know… that…Because of YOU Ananda has Managed to Survive one of the Most Uncertain Times of its Tenure  ~ We can not thank you enough for your enormous patience, understanding and support. From your incoming calls, comments on social media, direct messages across various channels, emails […]

CUSTOMER HEARTFELT RESPONSES

Here are a small fraction of the heartfelt responses we have received following the notice of our business closure and liquidation sale. We offer all of you a deserved shout out for being the improbable,  most essential, significant, factor in creating the Dream you are voicing to us: Hope for a Sustainable Future and Provider […]

Thank You For your Support

Thank You For your Support Since 2004 The Ananda Apothecary is Closing Business   SAD BUT TRUE As previously disclosed, The Ananda Apothecary has been greatly affected by to the global health situation. Bottom line is, we were increasing growing slim on product with no resupply any time soon. We are unable to get goods […]

Spring Cleaning Special

* SPRING CLEANING SPECIAL * *OFFERS VALID APRIL 24 – MAY 2, OR UNTIL SUPPLIES LAST. SOME RESTRICTIONS APPLY. WE’RE GIVING OILS AWAY Get Yours Today! WITH ANY PURCHASE THAT FITS YOUR BUDGET GET UP TO THREE OF YOUR ALL TIME FAVORITE OILS FREE *We have limited supplies due to overseas shipping restrictions. Order now while supplies last. ALSO […]